"Mother-In-Law" accomplished what few songs ever do; it aced both the pop and the R&B charts the spring of 1961. The Allen Toussaint song and production took Ernie K-Doe to heights he never saw again. It was his first and last Top 40 hit and anointed him the stigmatic "one-hit wonder" tag. Benny Spellman, who later had a lesser hit entitled "Lipstick Traces" (1962), performs the bass voice on this slap at mother-in-laws. K. Doe sings Toussaint's words from the personal experience of enduring a real-life "mother" of a mother-in-law himself. He actually found the song in Toussaint's trashcan; the then budding writer/producer had tossed it out with the garbage, and K-Doe had to practically beg Toussaint to let him record the song. It was K-Doe's third single for Minit Records.